B Lymphocyte-Specific, Cre-mediated Mutagenesis in Mice

To determine the efficiency and specificity of Cre-mediated deletion in B cells, CD19-Cre mice were crossed with mice bearing a DNA polymerase b gene (polb) in ... SkiptoMainContent Advertisement Journals Books SearchMenu Menu NavbarSearchFilter NucleicAcidsResearchThisissueNARJournals ScienceandMathematicsBooksJournalsOxfordAcademic MobileMicrositeSearchTerm Search SignIn Issues Sectionbrowse ChemicalBiologyandNucleicAcidChemistry ComputationalBiology DataResourcesandAnalyses GeneRegulation,ChromatinandEpigenetics GenomeIntegrity,RepairandReplication Genomics MolecularBiology NucleicAcidEnzymes RNAandRNA-proteincomplexes StructuralBiology SyntheticBiologyandBioengineering MethodsOnline SurveysandSummaries Database WebServer Advancearticles Submit AuthorGuidelines SubmissionSite OpenAccess Purchase About AboutNucleicAcidsResearch EditorialBoard InformationofReferees AdvertisingandCorporateServices JournalsCareerNetwork Alerts Policies Self-ArchivingPolicy DispatchDates JournalsonOxfordAcademic BooksonOxfordAcademic NARJournals Issues Sectionbrowse ChemicalBiologyandNucleicAcidChemistry ComputationalBiology DataResourcesandAnalyses GeneRegulation,ChromatinandEpigenetics GenomeIntegrity,RepairandReplication Genomics MolecularBiology NucleicAcidEnzymes RNAandRNA-proteincomplexes StructuralBiology SyntheticBiologyandBioengineering MethodsOnline SurveysandSummaries Database WebServer Advancearticles Submit AuthorGuidelines SubmissionSite OpenAccess Purchase About AboutNucleicAcidsResearch EditorialBoard InformationofReferees AdvertisingandCorporateServices JournalsCareerNetwork Alerts Policies Self-ArchivingPolicy DispatchDates Close NavbarSearchFilter NucleicAcidsResearchThisissueNARJournals ScienceandMathematicsBooksJournalsOxfordAcademic MicrositeSearchTerm Search AdvancedSearch SearchMenu ArticleNavigation Closemobilesearchnavigation ArticleNavigation Volume25 Issue6 1March1997 ArticleContents Abstract Acknowledgements References 95%.Acknowledgements WethankC.Göttlingerfortechnicalassistance,H.Ouforprovidingpolβmice,andF.Schwenkfordiscussionandcommentsonthemanuscript.SupportedbytheDeutscheForschungsgemeinschaftthroughSFB243andtheLandNordr-hein-Westfahlen.R.C.R.wassupportedbyfellowshipsfromtheHumanFrontierScienceProgramOrganization(HFSPO)andKölnerVereinzurForderungderImmunologie.References 1ThomasK.R., CappechiM.. , Cell, 1987, vol. 51 (pg. 503-512)CrossrefSearchADSPubMed 2KollerB.H., SmithiesO.. , Annu.Rev.Immunol., 1992, vol. 10 (pg. 705-730)CrossrefSearchADSPubMed 3SternbergN., HamiltonD.. , J.Mol.Biol., 1981, vol. 150 (pg. 467-486)CrossrefSearchADSPubMed 4SauerB., HendersonN.. , Proc.Natl.Acad.Sci.USA, 1988, vol. 85 (pg. 5166-5170)CrossrefSearchADS 5OuH., ZouY.-R., RajewskyK.. , Cell, 1993, vol. 73 (pg. 1155-1164)CrossrefSearchADSPubMed 6TorresR.M., FlaswinkelH., RethM., RajewskyK.. , Science, 1996, vol. 272 (pg. 1804-1808)CrossrefSearchADSPubMed 7Ramirez-SolisR.R, LiuP., BradleyA.. , Nature, 1995, vol. 378 (pg. 720-724)CrossrefSearchADSPubMed 8RajewskyK., OuH., KühnR., BetzU.A.K., MullerW., SchwenkF.. , J.Clin.Invest, 1996, vol. 98 (pg. 1-4)CrossrefSearchADSPubMed 9KühnR., SchwenkF., AguetM., RajewskyK.. , Science, 1995, vol. 269 (pg. 1427-1429)CrossrefSearchADSPubMed LaskoM., SauerB., MosingerB.Jr, LeeE.J., ManningR.W., YuS.H., MulderK.L., WestphalH.. , Proc.Natl.Acad.Sci.USA, 1992, vol. 89 (pg. 6232-6236)CrossrefSearchADS 11OrbanP.C., ChuiD., MarthJ.D.. , Proc.Natl.Acad.Sci.USA, 1992, vol. 89 (pg. 6861-6865)CrossrefSearchADS 12OuH., MarthJ.D., OrbanP.C., MossmannH., RajewskyK.. , Science, 1994, vol. 265 (pg. 103-106)CrossrefSearchADSPubMed 13HennetT., HagenF.K., TabakL.A., MarthJ.D.. , Proc.Natl.Acad.Sci.USA, 1995, vol. 92 (pg. 12070-12074)CrossrefSearchADS 14SchwenkF., BaronU., RajewskyK.. , NucleicAcidsRes, 1995, vol. 23 (pg. 5080-5081)CrossrefSearchADSPubMed 15LaskoM., PichelJ.O., GormanJ.R., SauerB., OkamotoY., LeeE., AltF., WestphalH.. , Proc.Natl.Acad.Sci.USA, 1996, vol. 93 (pg. 5860-5865)CrossrefSearchADS 16ZhouL-J, OrdD.C., HughesA.L., TedderT.. , J.Immunol., 1991, vol. 147 (pg. 1424-1432)PubMed 17KropI., deFougerollesA.R., HardyR.R., AllisonM., SchlisselM.S., FearonD.T.. , Eur.J.Immunol, 1996, vol. 26 (pg. 238-242)CrossrefSearchADSPubMed 18RickertR.C., RajewskyK., RoesJ.. , Nature, 1995, vol. 376 (pg. 352-355)CrossrefSearchADSPubMed 19RoesJ., RajewskyK.. , Int.Immunol., 1991, vol. 3 (pg. 1367-1371)CrossrefSearchADSPubMed 20ChenJ., LansfordR., StewartV., YoungF., AltF.W.. , Proc.Natl.Acad.Sci.USA, 1993, vol. 90 (pg. 4528-4532)CrossrefSearchADS 21Schwenk,F.,Sauer,B.,Kukoc,N.,Hoess,R.,Müller,W.,Kocks,C.,Kuhn,R.andRajewsky,K.(submitted).22JungS., RajewskyK., RadbruchA.. , Science, 1993, vol. 259 (pg. 984-987)CrossrefSearchADSPubMed  Authornotes +Presentaddress:DepartmentofBioligy,9500GilamanDrive,UniversityofCalifornia-SanDiego,LaJolla,CA92093,UDA§Presentaddress:UniversityCollegeLondonMedicalSchool,DepartmentofMedicine,RayneInstitute,5UniversityStreet,LondonWC1E6JJ,UK©1997OxfordUniversityPress©1997OxfordUniversityPress IssueSection: Articles Downloadallslides Comments 0Comments Comments(0) Addcomment Closecommentformmodal Iagreetothetermsandconditions. 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