Transcriptional Response Element (TRE) Clones
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Cloning & Clone Collection ... GLuc-ON™ TRE clones作用原理 應用範例:Analysis of TRE activity in GeneCopoeia TRE stable cell line 產品列表: ...
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TranscriptionalResponseElement(TRE)Clones
訊息傳遞路徑研究工具
GLuc-ON™transcriptionalresponseelement(TRE)clones用於在哺乳動物細胞系上進行快速靈敏的訊息傳遞路徑分析。
GLuc-ON™TREclone具non-viral或Lentiviral兩種形式,每個clone皆在minimalCMVpromoter的上游具多個重複的TRE序列。
產品特點:
活細胞分析-GLuc為分泌型蛋白,不需破細胞即可收集
即時研究-數據的產生十分快速,非常貼近即時活性
適合高通量研究使用
應用:
藥物研發或驗證:鑑定刺激或抑制目標訊息傳遞路徑的小分子
分析細胞對蛋白質或多肽的反應
分析細胞對激素的反應
功能基因組學研究:分析某個訊息傳遞路徑對基因活化、過度表達、沉默、敲除或突變的反應
病毒感染分析:分析細胞對病毒感染的反應
GLuc-ON™TREclones作用原理
應用範例:AnalysisofTREactivityinGeneCopoeiaTREstablecellline
產品列表:
TREnon-viralclone
TR100
CREBTREcloneforcAMP/PKAsignalingpathway
TR101
NFATTREcloneforPKC/Ca++signalingpathway
TR102
TCF/LEFTREcloneforWntsignalingpathway
TR103
Oct4TREcloneforOct4signalingpathway
TR104
HNF4TREcloneforHNF4signalingpathway
TR105
JNKTREcloneforSAPK/JNKsignalingpathway
TR106
PKCTREcloneforPKC/MAPKsignalingpathway
TR107
EGR1TREcloneforEGR1pathway
TR109
MEF2TREcloneforMEF2signalingpathway
TR110
ERSETREcloneforERstresspathway
TR111
GRTREcloneforglucocorticoidreceptorsignalingpathway
TR112
PPARTREcloneforperoxisomeproliferator-activatedreceptorsignalingpathway
TR113
PRTREcloneforprogesteronereceptorsignalingpathway
TR114
LXRaTREcloneforliverXreceptorsignalingpathway
TR115
NFκBTREcloneforNFκB-regulatedsignalingpathway
SEAP-PA01
NFκBTREcloneforNFκB-regulatedsignalingpathway
TR001
TREnegativecontrolclone
GAPDH-PG02
GAPDHpositivecontrolclone
TREnon-viralclone
TR200
CREBTRElentiviralcloneforcAMP/PKAsignalingpathway
TR201
NFATTRElentiviralcloneforPKC/Ca++signalingpathway
TR202
TCF/LEFTRElentiviralcloneforWntsignalingpathway
TR206
PKCTRElentiviralcloneforPKC/MAPKsignalingpathway
TR207
EGR1lentiviralTREcloneforEGR1pathway
TR002
TREnegativecontrollentiviralclone
TREStablecellline
SL401
HumancelllineHEK293TstablyexpressingPKC-GLuc
SL402
HumancelllineHEK293TstablyexpressingNFAT-GLuc
SL403
HumancelllineHEK293TstablyexpressingTCF/LEF-GLuc
SL404
HumancelllineHEK293TstablyexpressingNEG-GLuc
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