Side Effects of Loniten (Minoxidil Tablets, USP), Warnings, Uses

Loniten (minoxidil) is an antihypertensive peripheral vasodilator used only in the treatment of hypertension that is symptomatic or associated with target ... Loniten GenericName:minoxidiltablets,uspBrandName:Loniten DrugClass:Vasodilators MedicalEditor: JohnP.Cunha,DO,FACOEP LastupdatedonRxList:3/10/2022 home drugsa-zlist Loniten(MinoxidilTablets,USP)sideeffectsdrugcenter RelatedDrugs Apresazide Atacand AtacandHCT Capozide Cardura CarduraXL Edecrin Hyzaar IrbesartanGeneric Lotensin LotensinHct Methyldopa Midamor Monopril MonoprilHCT Prinivil Zestril HealthResources HighBloodPressure(Hypertension) PROFESSIONAL CONSUMER SIDEEFFECTS Overview ConsumerInformation ProfessionalInformation LonitenSideEffectsCenter MedicalEditor:JohnP.Cunha,DO,FACOEP WhatIsLoniten? Loniten(minoxidil)isanantihypertensiveperipheralvasodilatorusedonlyinthetreatmentofhypertensionthatissymptomaticorassociatedwithtargetorgandamageandisnotmanageablewithmaximumtherapeuticdosesofadiureticplustwootherantihypertensivedrugs. WhatAreSideEffectsofLoniten? CommonsideeffectsofLoniteninclude:dizzinessorlightheadednessasyourbodyadjuststothemedication,increasedgrowthordarkeningoffinebodyhairs(thiswillusuallyreturntonormalwithin1to6monthsafterstoppingthismedication),rash,lowbloodplateletcount,lowbloodwhitecellcount,nausea,vomiting,andbreasttenderness. DosageforLoniten/h4> TherecommendedinitialadultdosageofLonitentabletsis5mggivenasasingledailydose. WhatDrugs,Substances,orSupplementsInteractwithLoniten? Lonitenmayinteractwithguanethidine.Tellyourdoctorallmedicationsandsupplementsyouuse. LonitenDuringPregnancyorBreastfeeding Duringpregnancy,Lonitenshouldbetakenonlyifprescribed.Thisdrugisnotrecommendedforusewhilebreastfeeding. AdditionalInformation OurLoniten(minoxidil)SideEffectsDrugCenterprovidesacomprehensiveviewofavailabledruginformationonthepotentialsideeffectswhentakingthismedication. Thisisnotacompletelistofsideeffectsandothersmayoccur.Callyourdoctorformedicaladviceaboutsideeffects.YoumayreportsideeffectstoFDAat1-800-FDA-1088. QUESTION Saltandsodiumarethesame. SeeAnswer LonitenConsumerInformation Getemergencymedicalhelpifyouhavesignsofanallergicreaction:hives;difficultybreathing;swellingofyourface,lips,tongue,orthroat. Callyourdoctoratonceifyouhave: neworworseningchestpain; chestpainspreadingtoyourjaworshoulder; fastorpoundingheartbeats; swellinginyourlegs,ankles,orfeet; rapidweightgain,especiallyinyourfaceandmidsection; shortnessofbreath; alight-headedfeeling,likeyoumightpassout; fluidbuild-upinthelungs--painwhenyoubreathe,feelingshortofbreathwhilelyingdown,wheezing,gaspingforbreath,coughwithfoamymucus;or severeskinreaction--fever,sorethroat,swellinginyourfaceortongue,burninginyoureyes,skinpain,followedbyaredorpurpleskinrashthatspreads(especiallyinthefaceorupperbody)andcausesblisteringandpeeling. Commonsideeffectsmayinclude: changesincolor,length,orthicknessofbodyorfacialhair; nausea,vomiting; rash;or breastpainortenderness. Thisisnotacompletelistofsideeffectsandothersmayoccur.Callyourdoctorformedicaladviceaboutsideeffects.YoumayreportsideeffectstoFDAat1-800-FDA-1088. ReadtheentiredetailedpatientmonographforLoniten(MinoxidilTablets,USP)LearnMore» SLIDESHOW HowtoLowerBloodPressure:ExerciseTips SeeSlideshow LonitenProfessionalInformation SIDEEFFECTS SaltandWaterRetention (seeWARNINGS:ConcomitantUseofAdequateDiureticis Required)—Temporaryedemadevelopedin7%ofpatientswhowerenot edematousatthestartoftherapy. Pericarditis,PericardialEffusionAndTamponade (seeWARNINGS). Dermatologic Hypertrichosis—Elongation,thickening,andenhancedpigmentation offinebodyhairareseeninabout80%ofpatientstakingLONITENTablets. Thisdevelopswithin3to6weeksafterstartingtherapy.Itisusuallyfirst noticedonthetemples,betweentheeyebrows,betweenthehairlineandthe eyebrows,orintheside-burnareaoftheupperlateralcheek,laterextending totheback,arms,legs,andscalp.UpondiscontinuationofLONITEN,newhair growthstops,but1to6monthsmayberequiredforrestorationtopretreatment appearance.Noendocrineabnormalitieshavebeenfoundtoexplaintheabnormal hairgrowth;thus,itishypertrichosiswithoutvirilism.Hairgrowthis especiallydisturbingtochildrenandwomenandsuchpatientsshouldbe thoroughlyinformedaboutthiseffectbeforetherapywithLONITENisbegun. Allergic—Rasheshavebeenreported,includingrare reportsofbullouseruptions,toxicepidermalnecrolysis,andStevens-Johnson Syndrome. Hematologic Thrombocytopeniaandleukopenia(WBC<3000/mm³) haverarelybeenreported. Gastrointestinal Nauseaand/orvomitinghasbeenreported.Inclinical trialstheincidenceofnauseaandvomitingassociatedwiththeunderlying diseasehasshownadecreasefrompretriallevels. Miscellaneous Breasttenderness—Thisdevelopedinlessthan1%of patients. AlteredLaboratoryFindings (a)ECGchanges—Changesindirectionandmagnitudeofthe ECGT-wavesoccurinapproximately60%ofpatientstreatedwithLONITEN.In rareinstancesalargenegativeamplitudeoftheT-wavemayencroachuponthe S-Tsegment,buttheS-Tsegmentisnotindependentlyaltered.Thesechanges usuallydisappearwithcontinuanceoftreatmentandreverttothepretreatment stateifLONITENisdiscontinued.Nosymptomshavebeenassociatedwiththese changes,norhavetherebeenalterationsinbloodcellcountsorinplasma enzymeconcentrationsthatwouldsuggestmyocardialdamage.Long-termtreatment ofpatientsmanifestingsuchchangeshasprovidednoevidenceofdeteriorating cardiacfunction.Atpresentthechangesappeartobenonspecificandwithout identifiableclinicalsignificance.(b)Effectsofhemodilution—hematocrit, hemoglobinanderythrocytecountusuallyfallabout7%initiallyandthen recovertopretreatmentlevels.(c)Other—Alkalinephosphataseincreased varyinglywithoutotherevidenceofliverorboneabnormality.Serumcreatinine increasedanaverageof6%andBUNslightlymore,butlaterdeclinedto pretreatmentlevels. ReadtheentireFDAprescribinginformationforLoniten(MinoxidilTablets,USP)ReadMore» ©LonitenPatientInformationissuppliedbyCernerMultum,Inc.andLonitenConsumerinformationissuppliedbyFirstDatabank,Inc.,usedunderlicenseandsubjecttotheirrespectivecopyrights. HealthSolutionsFromOurSponsors PenisCurvedWhenErect CouldIhaveCAD? TreatBentFingers TreatHR+,HER2-MBC TiredofDandruff? LifewithCancer PillIdentifierToolQuick,Easy,PillIdentification DrugInteractionToolCheckPotentialDrugInteractions PharmacyLocatorToolIncluding24Hour,Pharmacies LonitenDrugImprint 005915642_PB round,white,imprintedwith2.5,DAN5642 005915643_PB round,white,imprintedwith10,DAN5643 422910618_PB round,white,imprintedwith2.5,MP84 422910619_PB round,white,imprintedwith10,MP89 498840256_PB round,white,imprintedwithpar256,MINOXIDIL21/2 498840257_PB round,white,imprintedwithpar257,MINOXIDIL10 534890386_PB round,white,imprintedwith2.5,MP84 534890387_PB round,white,imprintedwith10,MP89 Minoxidil10mg-WAT round,white,imprintedwith10,DAN5643 Minoxidil2.5mg-WAT round,white,imprintedwith2.5,DAN5642