Genomics - Latest research and news | Nature

Genomics is the study of the full genetic complement of an organism (the genome). It employs recombinant DNA, DNA sequencing methods, and bioinformatics to ... Skiptomaincontent Thankyouforvisitingnature.com.YouareusingabrowserversionwithlimitedsupportforCSS.Toobtain thebestexperience,werecommendyouuseamoreuptodatebrowser(orturnoffcompatibilitymodein InternetExplorer).Inthemeantime,toensurecontinuedsupport,wearedisplayingthesitewithoutstyles andJavaScript. Advertisement nature subjects genomics Atom RSSFeed Genomics Definition Genomicsisthestudyofthefullgeneticcomplementofanorganism(thegenome).ItemploysrecombinantDNA,DNAsequencingmethods,andbioinformaticstosequence,assemble,andanalysethestructureandfunctionofgenomes. RelatedSubjects Comparativegenomics Conservationgenomics Epigenomics Genomeassemblyalgorithms Genomeevolution Medicalgenomics Metagenomics Mobileelements Nutrigenomics Personalizedmedicine Pharmacogenomics Phylogenomics Transcriptomics Showmore LatestResearchandReviews Research 29November2021 | OpenAccess Combiningschizophreniaanddepressionpolygenicriskscoresimprovesthegeneticpredictionoflithiumresponseinbipolardisorderpatients KlausOliverSchubert,AnbupalamThalamuthu & BernhardT.Baune TranslationalPsychiatry11,606 Research 26November2021 | OpenAccess Chloranthusgenomeprovidesinsightsintotheearlydiversificationofangiosperms Chloranthalesremainthelastlineageofcoreangiospermsthatlacksanucleargenomeassembly.Here,theauthorsreportthegenomeassemblyofChloranthusspicatusandshowitscontributiontodeepenourunderstandingondiversification,phylogeny,andgenomeevolutioninangiosperms. XingGuo,DongmingFang & HuanLiu NatureCommunications12,6930 Research 26November2021 | OpenAccess TheChloranthussessilifoliusgenomeprovidesinsightintoearlydiversificationofangiosperms Chloranthalesremainthelastlineageofcoreangiospermsthatlacksanucleargenomeassembly.Here,theauthorsreportthegenomeassemblyofChloranthussesilifoliusandshowthatbothhybridizationandincompletelineagesortingmayhavecontributedtothephylogeneticincongruitiesintheliterature. JianxiangMa,PengchuanSun & YongzhiYang NatureCommunications12,6929 Research 26November2021 | OpenAccess GenomicanalysisofchildhoodhearinglossintheYorubapopulationofNigeria AdebolajoAdeyemo,RabiaFaridi & IsabelleRoux EuropeanJournalofHumanGenetics,1-11 Research | 26November2021 Deeplearningenablesgeneticanalysisofthehumanthoracicaorta Genome-wideassociationanalysesidentifyvariantsassociatedwiththoracicaorticdiameter.Apolygenicscoreforascendingaorticdiameterwasassociatedwithadiagnosisofthoracicaorticaneurysminindependentsamples. JamesP.Pirruccello,MarkD.Chaffin & PatrickT.Ellinor NatureGenetics,1-12 Research 25November2021 | OpenAccess Molecularmechanismsandtopologicalconsequencesofdrasticchromosomalrearrangementsofmuntjacdeer Muntjacdeerunderwentrapidspeciesradiationanddramaticchromosomefusionswithinashortperiodoftime.Heretheauthorsrevealthatrepeatsequenceslikelymediatedillegitimaterecombinationtoresultinchromosomefusionsandthat3Dchromatinarchitecturearoundfusionsiteshavenosignificantchange,whilesignificantinteractionsacrossfusionsitesweregraduallyestablishedafterspeciation. YuanYin,HuizhongFan & FuwenWei NatureCommunications12,6858 AllResearch&Reviews NewsandComment ResearchHighlights | 29November2021 Impactofgeneticancestryonviralinfectionresponse AstudyinSciencereportsthegeneticdeterminantsofdifferencesinimmuneresponsestoviralinfectionbetweenindividualsofEuropeanandAfricanancestries. LindaKoch NatureReviewsGenetics,1 Correspondence 29November2021 | OpenAccess MPLS505CenhancesdrivermutationsatW515inessentialthrombocythemia LeilaN.Varghese,GonzaloCarreño-Tarragona & StefanN.Constantinescu BloodCancerJournal11,188 ResearchHighlights | 18November2021 Laterallymobilechromosomes AstudyinNatureCommunicationsshowsthathorizontaltransferofbacterialchromosomesbyphage-mediatedlateraltransductionrendersthemmoremobilethanmanyclassicallydefinedmobilegeneticelements,includingplasmidsandtransposons. DorothyClyde NatureReviewsGenetics,1 Comments&Opinion | 17November2021 Europe’sRomapeoplearevulnerabletopoorpracticeingenetics AnalysisofhowpapersanddatabasesarehandledandinterpretedshowsthatgeneticistsinEuropemuststampoutunethicalresearchpracticesathome,notjustabroad. VeronikaLipphardt,MihaiSurdu & GudrunA.Rappold Nature599,368-371 Editorial | 05November2021 Thelanguageofgenetics Thelanguageusedingeneticandmedicalresearchtodescribepopulationshasafraughthistory,andcurrentpracticesmustbesensitivelyconsideredwhenreportingongeneticcohortsandanalyses. NatureGenetics53,1519 Comments&Opinion | 05November2021 Misuseoftheterm‘trans-ethnic’ingenomicsresearch Aconcerningtrendingeneticsisthecommonuseoftheterm‘trans-ethnic’todescribeanalysesthatcombineorcompareseveralancestrallydiversepopulations.Inthiscommentary,wediscusshowthistermisinaccurateandalienating.Weproposethatgeneticistsavoidusingthetermtrans-ethnicentirelyandthatresearchersacrossdisciplinesreachanewconsensusaboutthebesttermstousetodescribethepopulationswestudy. MireilleKamariza,LorinCrawford & HilaryFinucane NatureGenetics53,1520-1521 AllNews&Comment Search Searcharticlesbysubject,keywordorauthor Showresultsfrom Alljournals Search Advancedsearch Quicklinks Explorearticlesbysubject Findajob Guidetoauthors Editorialpolicies