Phenylalkylamines

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New Adamantane Phenylalkylamines with σ-Receptor Binding ...2012年10月24日 · The synthesis of the adamantane phenylalkylamines 2a–d, 3a–c, ... Zamora, P. O.; Moody, T. W.; John, C. S. Increased binding to sigma ... Laughlin, T. M.; Tram, K. V.; Wilcox, G. L.; Birnbaum, A. K. Comparison of antiepileptic ...What are the subclasses of calcium channel blockers (CCBs)?Phenylalkylamines: Affect the atrioventricular (AV) node and peripheral vasculature equally; verapamil is the only available agent in this class. Benzothiazines: ...New generations of dihydropyridines for treatment of hypertensionThese α subunits bind DHP and non-DHPs including phenylalkylamines and ... groups of structurally unrelated non-DHP CCBs, the phenylalkylamines (typified by verapamil) and the ... Malhotra HS, Plosker GL. ... Facebook · Share on Twitter  ...New Generation Calcium Channel Blockers in Hypertensive Treatment2006年5月1日 · In contrast, phenylalkylamines bind to the specific region of the α1 subunit located at the inner ... Chobanian AV, Bakris GL, Black HR, et al.Defining the Drug-binding Site in the Human Multidrug Resistance P ...Verapamil and other phenylalkylamines are inhibitors of the L-type calcium ... Kenyon, G. L., and Bruice, T. W. (1977) Methods Enzymol. 47, 407– 430. 41.Defining the Drug-binding Site in the Human Multidrug Resistance P ...Verapamil and other phenylalkylamines are inhibitors of thel-type calcium channels (. 61. Hargreaves A.C. ... Kenyon G.L.; Bruice T.W.. Methods Enzymol. 1977 ...Calcimimetics with potent and selective activity on the parathyroid ...... (usually an EC80) were used, so it is unlikely that these phenylalkylamines acted as agonists, antagonists, or allosteric modulators at these other receptors.The Treatment of Hypertension in Adult Patients With Diabetes ...The third group, the phenylalkylamines, has similar vascular and cardiac effects as ... Bakris GL, Williams M, Dworkin L, Elliott WJ, Epstein M, Toto R, Tuttle K, ...Efficacy and Safety of Dual Calcium Channel Blockade for the ...2013年1月15日 · ... by their chemical structure (benzothiazepines and phenylalkylamines). ... GL. Sowers. JR . ASH position paper: treatment of hypertension in ...The spectrum of cutaneous reactions associated with calcium ...... CAs are divided into benzothiazepines (diltiazem), phenylalkylamines ( verapamil), ... Kubota K, Pearse GL, Inman WH, Vasodilation-related adverse events in ...